Protein Purification
MilliporeSigma™ Calbiochem™ Castanospermine, Castanospermum australe
Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins.
MilliporeSigma™ Calbiochem™ AICA-Riboside, 5'-Phosphate
A 5'-phosphorylated analog of membrane permeable AICA-Riboside that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase).
MilliporeSigma™ Calbiochem™ Bufalin
A cardiotonic steroid isolated from toads of Bufo species that potently inhibits ouabain-sensitive Na+,K+-ATPase activity (IC50 = 1.4 nM).
MilliporeSigma™ Calbiochem™ TRPM Antagonist, M8-An
A cell-permeable, readily bioavailable 2-picolinamide derivative that acts as a highly potent antagonist of transient receptor potential cation channel subfamily M member 8 (TRPM8; IC50 =
MilliporeSigma™ Calbiochem™ Caspase-3/7 Inhibitor II
The Caspase-3/7 Inhibitor II, also referenced under CAS 775289-20-8, controls the biological activity of Caspase-3/7. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ Akt Inhibitor V, Triciribine
The InSolution™ Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Akt Inhibitor II
The Akt Inhibitor II controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Cantharidic Acid
A potent inhibitor of protein phosphatase 2A (IC50 = 50 nM).
MilliporeSigma™ Calbiochem™ (+)-Abscisic Acid
An isoprenoid plant hormone that acts as a growth regulator affecting leaf and fruit abscission and increases permeability of plant cells to water.
MilliporeSigma™ Calbiochem™ NMD Inhibitor
A cell-permeable inhibitor of nonsense-mediated mRNA decay (NMD) that enhances the stability of premature termination codon mutated p53 mRNA in N417 and HDQP-1 cells.
MilliporeSigma™ Calbiochem™ Adenosine A1 Receptor Agonist I, CPA
A potent and selective agonist of adenosine A1 receptor (A1R) (Ki
MilliporeSigma™ Calbiochem™ Glutaminase Inhibitor II, BPTES
A cell-permeable, potent, selective, reversible, and uncompetitive allosteric inhibitor of kidney-type glutaminase (GLS1). Does not affect the activity of liver glutaminase.
MilliporeSigma™ Calbiochem™ ATGL Inhibitor, Atglistatin
A cell-permeable, selective inhibitor of adipose triglyceride lipase activity (IC50 = 700 nM).
MilliporeSigma™ Calbiochem™ Estrogen Receptor Antagonist, ICI 182,780
A cell-permeable estrogen antagonist. More effective than tamoxifen in reducing estrogen receptors in breast tumor cells.
MilliporeSigma™ Calbiochem™ RORγt Inverse Agonist II, GSK805
A cell-permeable, potent, non-toxic, inverse agonist of RORγt. Directly and reversibly interacts with the ligand binding domain of RORγt to block its transcriptional effects.